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Baum 12 and J. Llving 2. Three groups of monkeys were used in the present study. The protective immune response persists for at least six months after vaccination.
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All animals were challenged intrarectally at around five months after the final immunization with a pathogenic SHIVP3 for a maximum of six challenges. They also show that MVA prime followed by a gp trimer boost can provide a significant protection against intrarectal SHIV challenges. Tomaka 1 ; D.
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Schuitemaker 2. Globally, 1. Week 28 and 52 data showed Ad HIV mefro prime, and Ad We here present data on durability of immune responses.
Healthy, uninfected participants were randomized into seven vaccine regimens, or a placebo and administered Ad HIV double prime Weeks 0 and 12 and a double boost of either Ad Groups boosted with Ad All participants in Ad HIV prime with Ad Stephenson 1,2 ; J. Ansel 1 ; S. Walsh 1 ; C. Ananos 1 ; A.
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Grazia Pau 3 ; M. Seaman 1 ; B. Walker 2 ; H. Schuitemaker merto and D. Barouch 1,2. Data from Baseline, 28 and 52 were analyzed.
All vaccine regimens appeared to be well tolerated. Pain and fatigue were the most frequently reported solicited events. In this Phase 1 study, we demonstrate that Ad Further studies are required to test the protective efficacy of these shortened vaccine regimens. Wensing 1 ; K. Bosman 1 ; A.